Computer-Based Training for Mild Alzheimer's Disease

Posit Science

Status and phase: Completed; Phase 1

Conditions: Alzheimer's Disease

Treatments: Procedure: Computer-based Cognitive Training

Study type: Interventional

Funder types: Other; Industry

Identifiers

NCT00319891

OUT-109-2005

Details and patient eligibility

About

The primary objective of this study is to evaluate the effects of computer-based training program ("HiFi-AD") on the memory and cognitive abilities of individuals diagnosed with mild Alzheimer's Disease (AD).

Full description

The purpose of this study is to determine the extent to which computer-based cognitive remediation improves cognitive functions using standardized neuropsychological assessments relevant to AD; 2) the acceptability and feasibility of using computer-based cognitive remediation in an AD population.

Sex: All

Ages: 60 to 90 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Fluent in English.
• Mini-Mental Status Examination (MMSE) score of 22 or higher.
• Adequate visual capacity.
• Adequate hearing capacity.
• Has a caregiver with some computer experience.
• Willing and able to commit to the time requirement of the entire study.

Exclusion criteria

• Clinically significant cerebrovascular disease.
• Participant is planning to begin acetylcholinesterase inhibitor (AChEI) therapy.
• Participants with severe tremor.
• Axis 1 or 2 psychiatric disorders.
• History of substance abuse.
• History of head trauma.

Trial design

Primary purpose: Treatment

Allocation: Non-Randomized

Interventional model: Single Group Assignment

Masking: None (Open label)