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Computer-based Training of Face Recollection to Improve Face Recognition in Developmental Prosopagnosia

B

Boston VA Research Institute, Inc.

Status

Enrolling

Conditions

Developmental Prosopagnosia

Treatments

Behavioral: cognitive training

Study type

Interventional

Funder types

Other

Identifiers

NCT04799340
R21EY031000, R01EY032510
R21EY031000

Details and patient eligibility

About

This study will examine the effectiveness of a cognitive training intervention targeting face recollection, repetition lag training, at improving face recognition in Developmental Prosopagnosia.

Enrollment

60 estimated patients

Sex

All

Ages

18 to 90 years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

Developmental prosopagnosic participants will be included if they are...

  • aged 18-90,
  • have lifelong histories of face recognition difficulties that impact their everyday life (i.e., not associated with some event such as a stroke, seizure, etc)
  • score significantly below the mean on the famous faces test and Cambridge Face Memory Test

Exclusion criteria

Participants will be excluded from the study if they...

  • have a history of a significant neurological disorder including hydrocephalus, stroke, moderate to severe traumatic brain injury (TBI), severe neuromuscular diseases, or severe hypoxia due to cardiac arrest.
  • have impairments that interfere with cognitive performance, such as uncorrected hearing or vision, lack of English proficiency, musculoskeletal or other issues
  • have psychiatric disorders, such as schizophrenia, major depressive disorder, bipolar disorder, chronic intractable obsessive-compulsive disorder, or agoraphobia.
  • We will exclude individuals who are currently dependent on alcohol or other substances, as this may negatively impact cognitive performance.
  • We will exclude participants who currently are, or within the last 6 months, participating in a behavioral or pharmacological intervention.
  • Patients with a history of mild TBI or simple concussion will not be excluded as long as it was > 6 months ago and as long as they have not had repeated concussions (>5)
  • We will include individuals with a diagnosis of ADHD as long as their medication has been consistent for the past 6 months.

Trial design

Primary purpose

Treatment

Allocation

Randomized

Interventional model

Parallel Assignment

Masking

Double Blind

60 participants in 2 patient groups

holistic face training + repetition lag training
Experimental group
Treatment:
Behavioral: cognitive training
waitlist control
No Intervention group

Trial contacts and locations

1

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Central trial contact

Joseph M DeGutis, Ph.D.

Data sourced from clinicaltrials.gov

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