Computer-Guided Glucose Management Systems in Treating Patients With Hyperglycemia Who Have Undergone Blood and Bone Marrow Transplant

Fred Hutchinson Cancer Center (FHCC)

Status: Completed

Conditions: Malignant Neoplasm; Hyperglycemia

Treatments: Other: computer-assisted intervention

Study type: Interventional

Funder types: Other; NIH

Identifiers

NCT01236885

2425.00 (Other Identifier)

NCI-2010-01102 (Registry Identifier)

P30CA015704 (U.S. NIH Grant/Contract)

Details and patient eligibility

About

This clinical trial studies computer-guided glucose management systems in treating patients with hyperglycemia who have undergone blood and bone marrow transplant. A computer-guided glucose management system may help manage glucose levels in patients who have undergone blood or bone marrow transplant.

Full description

PRIMARY OBJECTIVES:

I. To examine the ability of computer-guided glucose management system (CGGMS) algorithms to control glucose within or close to current University of Washington Medical Center (UWMC) intensive care unit (ICU) targets (100 to 140 mg/dl) in non-critically ill bone marrow transplant (BMT) adult (age >= 18 years) patients.

OUTLINE:

Patients receive blood glucose management with intravenous (IV) insulin using Glucommander.

Enrollment: 19 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Post-transplant adult patients (age >= 18 years) on the BMT Service at UWMC

• Requiring insulin secondary to:

  • Known history of (h/o) type 2 diabetes mellitus
  • Two blood sugar values > 180 (point of care and/or am lab glycemia)
  • One blood sugar value > 250 (point of care or AM lab glycemia)

Exclusion criteria

• Critically ill patients (intensive care unit [ICU] admissions)
• Terminally ill patients
• Eastern Cooperative Oncology Group (ECOG) performance status > 3
• Previous type 1 diabetes mellitus
• Cognitively impaired patients, unable to consent

Trial design

Primary purpose: Supportive Care

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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19 participants in 1 patient group

Supportive care (Glucommander)

Experimental group

Description:

Patients receive blood glucose management with IV insulin using Glucommander.

Treatment:

Other: computer-assisted intervention