Computerised Assessment of Visual Neglect Symptoms in Peripersonal Space (KMS-Neglect 2)

Charité University Medicine Berlin

Status: Terminated

Conditions: Visual Neglect

Treatments: Other: Cathodal tDCS; Other: Sham tDCS

Study type: Interventional

Funder types: Other

Identifiers

NCT01740544

KMS-Neglect 2

Details and patient eligibility

About

Healthy subjects will undergo cathodal stimulation of the right posterior parietal Cortex (PPC) and assessment of neglect-like symptoms in the encircling monitor system (EMS) as well as in a standard clinical test (Test Battery for Attention Performance, TAP, Zimmermann & Fimm, 1993). The aim of this study is to investigate whether cathodal stimulation leads to poorer test performance.

Enrollment: 16 patients

Sex: All

Ages: 18 to 85 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Younger subjects

  • aged between 18 and 35 years
  • ability to provide written informed consent
  • right-handedness

• Elderly subjects

  • aged between 50 and 85 years
  • ability to provide written informed consent
  • right-handedness

Exclusion criteria

• Exclusion criteria for both groups:

• serious psychiatric disorders (including depression, psychosis) in the past
• severe neurological disorders (such as epilepsy, dementia, stroke) in the past
• current severe medical disorder
• drugs, medication or alcohol abuse at the time of the study
• severe traumatic brain injury or tumor in the past
• operations on the brain, trepanations
• metallic implants in the head / neck area (except in the mouth), such as screws, splinter, artificial cochlea, electrodes
• severe skin diseases (like eczema) or very sensitive skin in the head region in the past
• epilepsy in the family
• current use of neuroleptics, antiepileptics, antidepressants, L-dopa, benzo-diazepines
• current pregnancy or lactation
• current claustrophobia

Trial design

Primary purpose: Diagnostic

Allocation: Randomized

Interventional model: Crossover Assignment

Masking: Double Blind

---

16 participants in 4 patient groups

Cathodal tDCS in young study participants

Experimental group

Description:

Cathodal tDCS in young study participants

Treatment:

Other: Cathodal tDCS

Cathodal tDCS in elderly study participants

Experimental group

Description:

Cathodal tDCS in elderly study participants

Treatment:

Other: Cathodal tDCS

Sham tDCS in young study participants

Sham Comparator group

Description:

Sham tDCS in young study participants

Treatment:

Other: Sham tDCS

Sham tDCS in elderly study participants

Sham Comparator group

Description:

Sham tDCS in elderly study participants

Treatment:

Other: Sham tDCS