Computerized Intervention for Distress Intolerance

Auburn University

Status: Completed

Conditions: Cannabis Use Disorder

Treatments: Behavioral: Computerized Healthy Behaviors Intervention; Behavioral: Computerized Distress Intolerance Intervention

Study type: Interventional

Funder types: Other; NIH

Identifiers

NCT04173078

201720828

F31DA039644-01A1 (U.S. NIH Grant/Contract)

Details and patient eligibility

About

This study evaluates the impact of a computerized distress intolerance intervention relative to a control intervention on cannabis use-related behavior and neurophysiology.

Full description

Distress intolerant cannabis users were randomized to a computerized distress intolerance intervention or a control intervention. Primary and secondary outcomes consist of the treatment target, cannabis use-related behavior, and theoretically-relevant neurophysiological processes (i.e., cannabis cue reactivity, response inhibition).

Enrollment: 60 patients

Sex: All

Ages: 18 to 30 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Distress Intolerance Index score >= 20
• Average cannabis use frequency in the past year >= 2-3/week

Exclusion criteria

• Current suicidal ideation
• History of psychotic symptoms
• Bipolar-spectrum disorder without stabilization on medication for >= 3 months
• Change in psychotropic medication in the past month
• Current CBT for internalizing or substance use disorders

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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60 participants in 2 patient groups, including a placebo group

Computerized Distress Intolerance Intervention

Experimental group

Description:

Two, 1-hour computerized sessions that include psychoeducation about emotional avoidance, idiographic emotional exposure, and construction of idiographic implementation intentions to practice distress tolerance skills outside of session.

Treatment:

Behavioral: Computerized Distress Intolerance Intervention

Computerized Healthy Behaviors Intervention

Placebo Comparator group

Description:

Two, 1-hour computerized sessions that focus on psychoeducation about the importance of a healthy lifestyle.

Treatment:

Behavioral: Computerized Healthy Behaviors Intervention