Computerized Lung Sound Analysis (CLSA)

Smolle-Juettner Freyja, Prof MD

Status: Completed

Conditions: Pulmonary Fibrosis; Pneumothorax

Treatments: Device: Lung Sound Recording System

Study type: Interventional

Funder types: Other

Identifiers

NCT02771184

28-088 ex 15/16

Details and patient eligibility

About

This clinical trial is conducted within the research project 'Computerized Lung Sound Analysis'. The research goal is the development of a system enabling the automatic classification of lung sounds, which will result in a decision support system for physicians.

The objective of this trial is to create a small lung sound corpus, enabling the development of a prototype of the described system. Therefore, investigators record lung sounds with several lung sound transducers distributed on the posterior chest of human test subjects.

Full description

In this clinical trial investigators record lung sounds over the posterior chest of human test subjects. The subjects are either lung-healthy (control group) or subjects with pneumothorax condition or pulmonary fibrosis. The lung sounds are recorded in supine position on an examination table. A foam pad with several lung sound transducers is placed under the back of the subjects. During the recording the subjects wear a nose clip and hold a pneumotachograph with both hands. The subjects are instructed to breath at a certain airflow rate during inspiration, with natural breathing during expiration. For each subject investigators simultaneously record 30 seconds of the airflow signal and the lung sounds from 16 lung sound transducers.

Enrollment: 24 patients

Sex: All

Ages: 18+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

General:

• Smoker and non-smoker
• 'Lung-healthy' subjects (control group), subjects with pneumothorax or subjects with pulmonary fibrosis

Additional for 'lung-healthy' subjects:

• COPD < 3 (GOLD Criteria)

Exclusion criteria

General:

• Body Mass Index > 30
• Preceding thoracic surgery
• Non-cooperation of the subject
• Intubated or tracheostomized subjects

Additional for 'lung-healthy' subjects:

• Disease of the respiratory system
• Taking medication influencing the respiration

Trial design

Primary purpose: Basic Science

Allocation: Non-Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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24 participants in 3 patient groups

Lung-Healthy

Other group

Description:

Subjects with no diagnosed lung disease. The intervention is the recording of lung sounds with the Lung Sound Recording System.

Treatment:

Device: Lung Sound Recording System

Pneumothorax

Other group

Description:

Subjects with pneumothorax. The intervention is the recording of lung sounds with the Lung Sound Recording System.

Treatment:

Device: Lung Sound Recording System

Pulmonary Fibrosis

Other group

Description:

Subjects with pulmonary fibrosis. The intervention is the recording of lung sounds with the Lung Sound Recording System.

Treatment:

Device: Lung Sound Recording System