Concentrated Growth Factor Versus Platelet Rich Fibrin in Revitalization of Necrotic Young Permanent Incisors

Ahmad Elheeny

Status: Not yet enrolling

Conditions: Necrotic Pulp

Treatments: Procedure: revitalization by concentrated growth factor

Study type: Interventional

Funder types: Other

Identifiers

NCT05522270

320

Details and patient eligibility

About

Regenerative endodontic procedures (REPs) are the most recent proposal to manage immature permanent teeth with necrotic pulps. So in this study, the investigator will evaluate the clinical and radiographical revitalization success in necrotic young permanent anterior teeth of participants by using Concentrated Growth Factor versus Platelet-Rich Fibrin

Full description

has been entered

Enrollment: 60 estimated patients

Sex: All

Ages: 6 to 11 years old

Volunteers: Accepts Healthy Volunteers

Inclusion and exclusion criteria

Inclusion Criteria:

• Healthy patients with immature permanent incisors
• Presence of clinical signs and symptoms of necrosis or chronic apical periodontitis. The chronic apical periodontitis signs and symptoms include little discomfort with intermittent episodes of pus discharge through the sinus tract.

Exclusion Criteria

1. Abnormal tooth mobility.

• Positive history of allergic reaction, systemic diseases, severe emotional or behavioral problems.
• Unrestorable teeth
• Abnormal tooth mobility
• Children with systemic, severe behavioral, or emotional problems

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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60 participants in 2 patient groups

revitalization by concentrated growth factor

Experimental group

Description:

modified platelet concentrate

Treatment:

Procedure: revitalization by concentrated growth factor

revitalization by platelet rich fibrin

Active Comparator group

Description:

platelet concentrate

Treatment:

Procedure: revitalization by concentrated growth factor