Concentrated Growth Factors in Regenerative Therapy in Furcation Involvements in Humans

Jing Qiao

Status: Unknown

Conditions: Periodontal Regeneration; Furcation Defects; Concentrated Growth Factors

Treatments: Procedure: GTR + CGF + bone graft; Procedure: CGF + bone graft

Study type: Interventional

Funder types: Other

Identifiers

NCT03180658

81600868

Details and patient eligibility

About

Objective: To compare the effect of guided tissue regeneration (GTR) + concentrated growth factors (CGF) + bone graft and CGF + bone graft in the treat of II° furcations of human mandibular molars. Methods: At least thirty II°furcation involvements in mandibular molars will be included and randomly divided into two groups. The experimental group will accept GTR + CGF + bone graft therapy, and the control group will accept CGF + bone graft therapy. The clinical examination and cone beam computed tomography (CBCT) will be performed at baseline and 1 year post-surgery.

Enrollment: 30 estimated patients

Sex: All

Ages: 18 to 70 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• II° furcation involvements in mandibular molars
• after periodontal therapy.

Exclusion criteria

• not healthy

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

---

30 participants in 2 patient groups

experimental

Experimental group

Description:

GTR+CGF+bone graft, CGF

Treatment:

Procedure: GTR + CGF + bone graft

controlled

Active Comparator group

Description:

CGF+bone graft

Treatment:

Procedure: CGF + bone graft