Concomitant High-resolution Recording of Haemodynamic and Electrical Activities of Children With Typical or Atypical Absence Seizures

Centre Hospitalier Universitaire, Amiens

Status: Unknown

Conditions: Epilepsy

Treatments: Device: Near Infra Red Spectroscopy (NIRS); Device: Electroencephalography (EEG)

Study type: Observational

Funder types: Other

Identifiers

NCT02819427

PI2012_843_0025

Details and patient eligibility

About

This study, conducted in children with typical or atypical "absence" epilepsy, will consist of noninvasive recording of the metabolic activity of the brain concomitantly with electroencephalographic recording during seizures without the need for any additional examination. This examination will be performed by combining near-infrared spectroscopy (NIRS) optical imaging and Electroencephalography (EEG) in a simultaneous High-Resolution (HR) recording.

Surface electroencephalography (EEG) is a valuable tool to assess neuronal dysfunction from a functional point of view and is used in the routine follow-up of epileptic children. Optical imaging is a recent and promising medical imaging technique, which uses near-infrared light. This rapid, noninvasive and harmless quantitative technique can be easily used at the child's bedside or in the ward and provides metabolic information on brain functioning.

Enrollment: 10 patients

Sex: All

Ages: 3 to 14 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Children aged 3 to 14 years
• Featuring absence epilepsy with typical or atypical seizures characterized by the presence of spontaneous spike-wave flashes with standard EEG

Exclusion criteria

• All children with severe congenital malformation
• Any refusal of a parent or child
• Any child with a serious deterioration in the general condition and vital functions
• Any child with dermatitis of the face or scalp
• Children under 3 years old or over 14 years

Trial design

10 participants in 1 patient group

epilepsy

Description:

children with absence epilepsy presenting either typical or atypical seizures

Treatment:

Device: Electroencephalography (EEG)

Device: Near Infra Red Spectroscopy (NIRS)