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Concomitant Infection of Intestinal Parasites and Helicobacter Pylori

S

Sohag University

Status

Enrolling

Conditions

Dyspepsia Abdominal Burning Pain Diarrhea Dysentery

Treatments

Diagnostic Test: H.pylori stool antigen rapid test and stool parasitological examination

Study type

Observational

Funder types

Other

Identifiers

NCT05360940
Soh-Med-22-04-15

Details and patient eligibility

About

Intestinal parasitic infections such as Giardia lamblia, Entamoeba histolyica and Enterobius Vermicularis are among the most common infections worldwide.So parasitic infections are considered one of the major health problems in the world especially in developing countries.

Helicobacter pylori is a gram-negative,helical-shaped,motile bacillus bacterium,which colonizes the gastric mucosa.

H.pylori bacterium secretes urease,a special enzyme that converts urea to ammonia.

Ammonia reduces the stomach's acidity .This risk factor allows pathogenic intestinal protozoa such as G.lamblia to take the opportunity to cross through the stomach's increased pH and cause disease.

Enrollment

200 estimated patients

Sex

All

Ages

1+ year old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

  • patients complaining of dyspepsia , abdominal burning pain,diarrhea,dysentery,of persons of any age or sex group.

Exclusion criteria

  • patients taking antibiotics within the previous four weeks, proton pump inhibitors within the previous two weeks, or anti-parasitic drugs within the previous two weeks.

Trial design

200 participants in 2 patient groups

A
Description:
100 positive stool samples for H.pylori
Treatment:
Diagnostic Test: H.pylori stool antigen rapid test and stool parasitological examination
B
Description:
100 negative stool samples for H.pylori
Treatment:
Diagnostic Test: H.pylori stool antigen rapid test and stool parasitological examination

Trial contacts and locations

1

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Central trial contact

Asmaa Nabil Abouzeid

Data sourced from clinicaltrials.gov

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