ClinicalTrials.Veeva

Menu

Concomitant Therapy of H. Pylori

T

The Catholic University of Korea

Status and phase

Unknown
Phase 4

Conditions

Gastritis, Gastric Ulcer, and Duodenal Ulcer

Treatments

Drug: amoxicillin, clarithromycin, metronidazole, rabeprazole

Study type

Interventional

Funder types

Other

Identifiers

NCT01922765
concomitant

Details and patient eligibility

About

If we compare eradication rate of Helicobacter pylori divided to 4 groups: amoxicillin, rabeprazole, clarithromycin(AOC), amoxicillin, rabeprazole, metronidazole(AOM), treated with amoxicillin, rabeprazole for 5 day, followed by clarithromycin, metronidazole, rabeprazole for 5 days(sequential), amoxicillin, clarithromycin, metronidazole, rabeprazole(concomitant), then the eradication rate of concomitant group will be the highest.

Full description

  • Subject: The patient of gastritis, gastric ulcer, and duodenal ulcer infected with Helicobacter pylori
  • 170 subjects per group
  • Eradication regimens are as follows: AOC group, treated with amoxicillin, rabeprazole, clarithromycin for 7 days; AOM group, treated with amoxicillin, rabeprazole, metronidazole for 7 days; sequential group, treated with amoxicillin, rabeprazole for 5 day, followed by clarithromycin, metronidazole, rabeprazole for 5 days; concomitant group, treated with amoxicillin, clarithromycin, metronidazole, rabeprazole for 7 days

Enrollment

540 estimated patients

Sex

All

Ages

19 to 75 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

  • patients infected with Helicobacter pylori

Exclusion criteria

  • cancer
  • pregnancy
  • formerly treated with eradication

Trial design

Primary purpose

Treatment

Allocation

Randomized

Interventional model

Parallel Assignment

Masking

None (Open label)

540 participants in 4 patient groups

AOC group
Experimental group
Description:
AOC group: treated with amoxicillin, rabeprazole, clarithromycin for 7 days
Treatment:
Drug: amoxicillin, clarithromycin, metronidazole, rabeprazole
AOM group
Experimental group
Description:
AOM group: treated with amoxicillin, rabeprazole, metronidazole for 7 days
Treatment:
Drug: amoxicillin, clarithromycin, metronidazole, rabeprazole
Sequential group
Experimental group
Description:
Sequential group: treated with amoxicillin, rabeprazole for 5 day, followed by clarithromycin, metronidazole, rabeprazole for 5 days
Treatment:
Drug: amoxicillin, clarithromycin, metronidazole, rabeprazole
concomitant group
Experimental group
Description:
concomitant group: treated with amoxicillin, clarithromycin, metronidazole, rabeprazole for 7 days
Treatment:
Drug: amoxicillin, clarithromycin, metronidazole, rabeprazole

Trial contacts and locations

1

Loading...

Data sourced from clinicaltrials.gov

Clinical trials

Find clinical trialsTrials by location
© Copyright 2024 Veeva Systems