Concurrent Oxytocin With Membrane Sweeping Versus Dinoprostone Pessary in Labor Induction of Nulliparas at Term

Seoul National University

Status: Completed

Conditions: Failed Induction of Labor

Treatments: Drug: Oxytocin; Drug: Dinoprostone; Procedure: Membrane sweeping

Study type: Interventional

Funder types: Other

Identifiers

NCT02416583

SWP_PG_N2

Details and patient eligibility

About

To compare concurrent oxytocin with membrane sweeping versus dinoprostone pessary in labor induction for nulliparas at term with an unfavorable cervix

Enrollment: 140 patients

Sex: Female

Volunteers: No Healthy Volunteers

Inclusion criteria

• singleton pregnancy
• Nulliparous women
• gestational age >=37.0 weeks
• Bishop score <=6
• intact amniotic membrane
• absence of labor
• live fetus with vertex presentation
• no previous uterine surgical procedure

Exclusion criteria

• Multiple pregnancy
• Placenta previa

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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140 participants in 2 patient groups

Oxytocin & Membrane sweeping

Active Comparator group

Description:

Women assigned to "Concurrent oxytocin with membrane sweeping" had their cervix swept by inserting the examining finger as high as possible past the internal cervical os, followed by oxytocin infusion the next day

Treatment:

Procedure: Membrane sweeping

Drug: Oxytocin

Oxytocin & Dinoprostone

Active Comparator group

Description:

For women assigned to "Concurrent oxytocin with dinoprostone vaginal insert": The 10mg dinoprostone vaginal insert were placed in the posterior fornix for cervical ripening, followed by oxytocin infusion the next day

Treatment:

Drug: Dinoprostone

Drug: Oxytocin