Concurrent Transcranial Direct Current Stimulation and Gait Training in Parkinson's Disease

National Yang Ming Chiao Tung University

Status: Unknown

Conditions: Parkinson's Disease

Treatments: Other: Sham tDCS plus gait training; Other: Active tDCS plus gait training

Study type: Interventional

Funder types: Other

Identifiers

NCT04041661

19MMHIS113e

Details and patient eligibility

About

To investigate the effect of concurrent transcranial direct current stimulation and gait training on gait performance when doing the cognitive dual-task in people with Parkinson's Disease.

Enrollment: 30 estimated patients

Sex: All

Ages: 50 to 80 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Diagnosed with idiopathic PD
• Hoehn and Yahr stages I-III
• Mini Mental Status Examination (MMSE) score ≧ 24
• Could walk 10m independently with or without gait aid

Exclusion criteria

• Concurrent medication likely to affect mental performance
• tDCS contraindication
• Significant neurological, vestibular, visual disorders or psychiatric illness
• Musculoskeletal or cardiopulmonary disease
• Sensory system pathology

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

---

30 participants in 2 patient groups

Active tDCS plus gait training group

Experimental group

Description:

Participants in Active tDCS plus gait training group will execute Active tDCS on left dorsolateral prefrontal cortex which combined with treadmill, 12 times per week, least 4 weeks.

Treatment:

Other: Active tDCS plus gait training

Sham tDCS plus gait training group

Sham Comparator group

Description:

Participants in Sham tDCS plus gait training group will executeSham tDCS on left dorsolateral prefrontal cortex which combined with treadmill, 12 times per week, least 4 weeks.

Treatment:

Other: Sham tDCS plus gait training