Confounding Factors in Ocular Surface Microbiome Research (CoFa)

Universitaire Ziekenhuizen KU Leuven

Status: Completed

Conditions: Ocular Surface Microbiome

Treatments: Diagnostic Test: Conjunctival swab

Study type: Interventional

Funder types: Other

Identifiers

NCT04193917

S63155

Details and patient eligibility

About

To elucidate confounding factors in ocular surface microbiome research and to confirm the presence of a core ocular surface microbiome and its temporal stability.

Full description

The investigator will take a conjunctival sample of both eyes of a group of volunteers together with an extensive questionnaire. Furthermore, 50 volunteers will be sampled repeatedly during one year or two years.

Enrollment: 450 patients

Sex: All

Ages: 18+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• The subject is fluent in written and verbal Dutch
• The subject is capable of giving informed consent

Exclusion criteria

• Use of glaucoma drops
• Use of antibiotic drops < 1 month before sampling

Trial design

Primary purpose: Diagnostic

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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450 participants in 1 patient group

conjunctival swab

Other group

Description:

A conjunctival swab of both eyes will be taken

Treatment:

Diagnostic Test: Conjunctival swab