Congenital Heart Surgery in Pediatric Patients With Beta-Thalassemia Major

Ain Shams University

Status: Completed

Conditions: Hemolysis

Treatments: Diagnostic Test: Hemolysis

Study type: Observational

Funder types: Other

Identifiers

NCT04367701

Thalassemia CHD

Details and patient eligibility

About

Authors compared incidence of Hemolysis on Cardiopulmonary Bypass surgery for repair of congenital heart disease in Pediatric Patients between patients with thalassemia major and control group

Enrollment: 41 patients

Sex: All

Ages: 6 months to 12 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Pediatric Patients with thalassemia major.
• Pediatric Patients with congenital heart disease undergoing surgical repair.

Exclusion criteria

• known hepatic or renal disease
• uncontrolled active hemolytic reaction
• emergency surgery
• redo surgery

Trial design

41 participants in 2 patient groups

Thalassemia group

Description:

16 pediatric patients with thalassemia major undergoing surgery for repair of congenital heart disease. Authors measure hemolysis by free plasma hemoglobin concentration.

Treatment:

Diagnostic Test: Hemolysis

Control group

Description:

25 pediatric patients with demographic data related to those in thalassemia group, undergoing surgery for repair of congenital heart disease. Authors measure hemolysis by free plasma hemoglobin concentration

Treatment:

Diagnostic Test: Hemolysis