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Conjoined Twins: a Report of Four Cases. (CT)

A

Assiut University

Status

Completed

Conditions

Conjoined Twin

Treatments

Procedure: Conjoined twin separation surgery

Study type

Observational

Funder types

Other

Identifiers

NCT03388684
17300170

Details and patient eligibility

About

The present study aims to report our experience in conjoined twin separation surgery in Assuit university and pediatric hospital, Assiut university, Assiut, Egypt over a period of 20 years.

Full description

A conjoined twin is a subset of monozygotic twin gestation. It's a rare phenomenon with an incidence of 1 in 50,000 to 1:100,000 births with the higher incidence in Africa and Southwest Asia. Based on the terminology proposed by Spencer and colleagues, conjoined twins are classified according to the most prominent site of conjunction into three major groups; First, twins with a ventral union; [cephalopagus (head), thoracopagus (Thorax), omphalopagus (Abdomen) and ischiopagus (pelvis)]. Second; twins with a dorsal union; [pygopagus (sacrum), rachipagus (spine, back) and craniopagus (cranium)] and lastly; twins with a lateral union that is referred to as parapagus (side). Depending on the aspect of the embryonic disc, the most common types are thoracopagus (19%).

Surgical separation of conjoined twins is extremely challenging taking in consideration the high perioperative risk. The low incidence of such surgeries and anatomical variations in each type of conjoined twins makes each separation surgery a unique experience.

Enrollment

4 patients

Sex

All

Ages

1 to 30 days old

Volunteers

No Healthy Volunteers

Inclusion criteria

  • conjoined twins
  • symmetrical or
  • asymmetrical.

Exclusion criteria

  • conjoined twins incompatible with life
  • conjoined twins with decapitating medical illness.

Trial contacts and locations

0

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Data sourced from clinicaltrials.gov

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