Conjugated Linoleic Acid in Obese Women (CLA)

Universidade Estadual de Londrina

Status: Completed

Conditions: Lipid Metabolism Disorders; Obesity

Treatments: Behavioral: Placebo; Dietary Supplement: CLA

Study type: Interventional

Funder types: Other

Identifiers

NCT02529046

ESCyrino

Details and patient eligibility

About

In this trial, the investigators analyzed the effects of eight weeks of CLA supplementation associated with aerobic exercise on body fat and lipid profile in obese women.

Full description

The aim of this investigation was to analyze the effects of eight weeks of CLA supplementation associated with aerobic exercise on body fat and lipid profile in obese women. The investigators performed a randomized, double-blinded and placebo-controlled trial with 28 obese women who received 3.2 g/d of CLA or 4 g/d of olive oil (placebo group) while performing an 8-week protocol of aerobic exercise. Dietary intake (food record), body fat (DXA) and biochemical analysis (blood sample) were assessed before and after the intervention period.

Enrollment: 28 patients

Sex: Female

Ages: 18 to 35 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Had no signs or symptoms of disease
• No orthopedic injuries
• Must be inactive or moderately active (defined as performing any type of physical exercise less than twice a week)
• Must be non-smokers
• Must be free from the use of ergogenic aids
• Had no metabolic disorders or chronic degenerative diseases
• Not use drug therapy for body mass loss.

Exclusion criteria

• Had frequency to training sessions below 85% of the total sessions

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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28 participants in 2 patient groups, including a placebo group

Aerobic exercise associated with CLA

Active Comparator group

Description:

CLA group received supplementation at a dose of 3.2 g/day (mixture of isomers of CLA isomers predominantly c9, t11 - 50% and c12, t10 - 80%).

Treatment:

Dietary Supplement: CLA

Aerobic exercise

Placebo Comparator group

Description:

Placebo group received 4 g/day of olive oil.

Treatment:

Behavioral: Placebo