CONNACT OA Knee Cohort

Tan Tock Seng Hospital

Status: Not yet enrolling

Conditions: Osteoarthritis, Knee

Study type: Observational

Funder types: Other

Identifiers

NCT04942236

WHC/2020-00076

Details and patient eligibility

About

CONNACT OA knee cohort is a prospective longitudinal cohort study where we aim to collect sociodemographic, psychosocial, clinical, health utilization and cost data in order to better understand the Asian OA knee cohort and investigate for prognostic variables that can potentially influence a patients clinical outcome and treatment decisions.

In addition, the CONNACT OA knee cohort will form the basis for a cohort multiple randomized control trial (cmRCT) study design where multiple interventions can be tested in a randomized fashion. Each intervention is offered to a randomly selected sample of patients eligible for that intervention, who are then compared with the rest of the eligible patients from the cohort that are still being treated as usual.

Enrollment: 500 estimated patients

Sex: All

Ages: 46 to 99 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

1. Knee Osteoarthritis (based on NICE guidelines)
2. Age > 45 years
3. Community ambulator with or without walking aid
4. Conversant in English or Chinese

Exclusion criteria

1. Alternative diagnosis to Knee OA e.g. referred pain from spine or hip
2. Other forms of knee arthritis e.g. inflammatory, post-traumatic
3. Moderate to severe cognitive impairment e.g. dementia
4. Previous knee arthroplasty
5. Wheelchair bound patients
6. Medical conditions that will medically interfere with rehabilitation involvement e.g. decompensated heart failure, stroke with significant deficit, end stage renal failure