Connective Tissue Graft and Leucocyte - Platelet Rich Fibrin in Alveolar Ridge Preservation

G. d'Annunzio University

Status: Not yet enrolling

Conditions: Alveolar Socket Preservation

Treatments: Procedure: Connective tissue graft + L-PRF; Procedure: L-PRF

Study type: Interventional

Funder types: Other

Identifiers

NCT06663982

27102024

Details and patient eligibility

About

The purpose of our randomized controlled clinical trial is to evaluate radiographic bone dimensional changes and soft tissue healing and thickness after teeth extraction and the implementation of alveolar ridge preservation (RAP) procedures that will involve the application of L-PRF inside the socket in association with a connective tissue graft (CTG) used as a barrier with the periosteal inhibition technique (PI). The present experimental treatment (test group) will be compared with an active comparator (control group) which will involve the insertion of L-PRF alone inside the socket.

Enrollment: 34 estimated patients

Sex: All

Volunteers: No Healthy Volunteers

Inclusion and exclusion criteria

• Age > 18 years old;
• General good health (ASA I-II);
• Adequate oral hygiene (Full Mouth Plaque Score ≤ 20%, Full Mouth Bleeding Score ≤ 20%);
• Presence of one or more hopeless teeth requiring extraction.

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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34 participants in 2 patient groups

CTG + L-PRF

Experimental group

Treatment:

Procedure: Connective tissue graft + L-PRF

L-PRF

Active Comparator group

Treatment:

Procedure: L-PRF