Conotruncal Cardiac Defects and Nutrigenetic Etiopathogeny (CCOMET)

Central Hospital, Nancy, France

Status: Completed

Conditions: Conotruncal Cardiac Defects

Treatments: Biological: Bood sampling for biochemicals and genetic analysis

Study type: Observational

Funder types: Other

Identifiers

NCT01460316

2011-A00346-35

Details and patient eligibility

About

The investigators planned to study the etiopathogenic factors of conotruncal cardiac defects regarding the relations between the metabolic, the genetic and the environmental factors which lead to these cardiopathy.

Enrollment: 400 patients

Sex: All

Ages: 1+ month old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Conotruncal cardiac defects patients and theirs mothers
• Weight: > 3750 g

Exclusion criteria

• Syndromic conotruncal cardiac defects
• 22q11 deletion Holder's
• Patients whose mother's took anti-folates before and during first pregnancy semester

Trial design

400 participants in 2 patient groups

Conotruncal cardiac defects patients

Treatment:

Biological: Bood sampling for biochemicals and genetic analysis

Mothers of patients

Treatment:

Biological: Bood sampling for biochemicals and genetic analysis