Consequence of Injectable Platelets Rich Fibrin Versus Microosteopeforation on Root Resorption During Orthodontic Intrusion of Incisor Teeth

Al-Azhar University

Status and phase: Invitation-only; Phase 1

Conditions: Compare the Effect of Injectable Platelets Rich Fibrin and Micro-osteoperforations on Root Resorption During Orthodontic Intrusion of Incisors

Treatments: Combination Product: injectable platelet rich fibrin and microosteoperforation

Study type: Interventional

Funder types: Other

Identifiers

NCT05958498

922/91

Details and patient eligibility

About

Consequence of injectable platelets rich fibrin versus microosteopeforation on root resorption during orthodontic intrusion of incisor teeth

Full description

Consequence of injectable platelets rich fibrin versus microosteopeforation on root resorption during orthodontic intrusion of incisor teeth: A comparative clinical study

Enrollment: 18 estimated patients

Sex: All

Ages: 15 to 22 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• 1. Patients with age range between 12-16 years. 2. Overbite > 40% indicated for maxillary intrusion. 3. Mild to moderate crowding of upper incisors. 4. All permanent teeth erupted (excluding 3rd molars). 5. No previous orthodontic treatment. 6. Good oral hygiene with no previous periodontal surgery.

Exclusion criteria

1. • Transverse and/or vertical skeletal dysplasia or craniofacial malformation. 2. Retained primary or missing permanent teeth in the maxillary anterior area, and any kind of tooth/root shape anomaly.

2. Patients with root resorption, impacted canines, or dental anomalies. 4. Poor oral hygiene 5. Present or history of periodontal diseases. 6. Systemic diseases or regular use of medications that could interfere with orthodontic tooth movement.

3. History of trauma affecting the maxillary incisors. 8. Endodontically treated upper anterior teeth.

Trial design

Primary purpose: Basic Science

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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18 participants in 2 patient groups

Group I

Active Comparator group

Description:

who will receive intrusive arches after leveling and alignment assisted with i-PRF according to standardized protocol

Treatment:

Combination Product: injectable platelet rich fibrin and microosteoperforation

Group II

Active Comparator group

Description:

Will includes 9 patients who will receive intrusive utility arches after leveling and alignment assisted with (MOPs) according to standardized protocol.

Treatment:

Combination Product: injectable platelet rich fibrin and microosteoperforation