Consequences of Hypoglycemia on Intensive Care Unit (ICU) Patients

University Hospital Muenster

Status: Completed

Conditions: Critical Illness

Study type: Observational

Funder types: Other

Identifiers

NCT00662922

05-AnIt-07

Details and patient eligibility

About

Hypoglycemia occurs frequently during intensive blood glucose control in critically ill patients. The incidence of hypoglycaemia is associated with impaired outcome. However, it is hitherto unknown if hypoglycaemia itself predisposes patients to neurological impairment, e.g. cognitive dysfunction, or if it is the underlying medical condition that makes the patient prone to a high risk of hypoglycaemia and, concomitantly, neurocognitive impairment. Therefore we investigate neurocognitive function in patients who had hypoglycemias during their intensive care stay and compare the results to patients without hypoglycaemia whose medical conditions are matched to the hypoglycaemia patients.

Enrollment: 74 patients

Sex: All

Ages: 18 to 80 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• all patients

Exclusion criteria

• clinical diagnosis of diabetes mellitus
• brain injury of any kind prior to or upon ICU-admission
• pre-existing mental or psychiatric disorder
• terminal kidney or liver failure prior admission
• drug abuse,
• CPR > 5 min
• HIV
• Lues

Trial design

74 participants in 2 patient groups

1

Description:

patients with hypoglycemia during intensive care

2

Description:

patients without hypoglycemia during intensive care