Consistency of Carotid Doppler Blood Flow and Thermodilution Technique

Fudan University

Status: Enrolling

Conditions: Cardiac Surgery

Treatments: Behavioral: passive leg raising; Drug: Dobutamine

Study type: Interventional

Funder types: Other

Identifiers

NCT05944146

Cracard

Details and patient eligibility

About

Currently, the gold standard method to estimate CO is the thermodilution technique, pulmonary artery catheter (PAC) and PiCCO system included, however, the invasiveness and complexity of the thermodilution technique have limited their usefulness in many clinical scenarios. By measuring the carotid blood flow, continuous carotid doppler technique has been reported to noninvasively estimate cardiac output (CO) and other parameters related to cardiac contractility and fluid status in various cardiovascular disorders. However, to the best of our knowledge, few study has been reported to evaluate the consistency of this technique in cardiac surgery patients. The aim of this study is to evaluate the tracking ability of CO changes measured by continuous carotid doppler technique in cardiac surgery patients, use the thermodilution technique as the referenced.

Enrollment: 200 estimated patients

Sex: All

Ages: 18 to 80 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• adult cardiac surgery patients
• with thermodilution technique monitoring
• mechanical ventilation

Exclusion criteria

• life threatening arrhythmia
• severe valve regurgitation
• left ventricular ejection fraction less than 30%
• patients with mechanical circulatory support

Trial design

Primary purpose: Diagnostic

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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200 participants in 1 patient group

cardiac surgery patients with thermodilution technique monitoring

Experimental group

Treatment:

Drug: Dobutamine

Behavioral: passive leg raising