Construction of a Database for TMA

Soochow University

Status: Enrolling

Conditions: Thrombotic Microangiopathies

Treatments: Other: collection data

Study type: Observational

Funder types: Other

Identifiers

NCT05634928

SOOCHOW-HY-2022-13

Details and patient eligibility

About

Information about patients was collected by reviewing the Hitech case system and telephone and outpatient follow-up, and the case database was constructed by Epidata software. The sample size is expected to be 200 cases, the participating hospital is the First Affiliated Hospital of Soochow University, and the study time frame is from Dec 1, 2022, to Nov 31, 2027. The observation indexes of the study include the basic information of patients' age and gender and the clinical-related data of thrombotic microangiopathy.

Enrollment: 500 estimated patients

Sex: All

Volunteers: No Healthy Volunteers

Inclusion criteria

• The patient has elevated lactate dehydrogenase to more than twice the baseline value, platelets less than 20 or decreased by more than 50% within 24 hours, and more than 2% of schistocytes visible on a peripheral blood smear. Alternatively, pathological sections show extensive micro thrombosis.

Exclusion criteria

• The investigator considers the subject unable or unwilling to cooperate with the study procedures.

Trial design

500 participants in 1 patient group

TMA

Description:

TMA patients

Treatment:

Other: collection data