Construction of an Ultrasound Profile and a Mammographic Profile Corresponding to the Different Molecular Subtypes of Brest Cancer. A Retrospective Study (PROFILS)

Elsan

Status: Completed

Conditions: Breast Cancer

Study type: Observational

Funder types: Other

Identifiers

NCT05757232

Etude PROFILS

Details and patient eligibility

About

PROFILS is a retrospective, exploratory study on data collected in 203 breast cancer cases diagnosed during a national screening campaign from 2015 to 2018.

The aim of the study is to analyse histological, clinical and radiological data collected during the screening campaign to build an ultrasound profile and a mammographic profile corresponding to brest cancers' different molecular sub-types (Luminal A, Luminal B, HER2+, Triple negative) using the BI-RADS classification.

The study has the following objectives:

• To compare molecular profiles of breast cancers detected in a cohort of women diagnosed with tomosynthesis and ultrasound with molecular profiles of brest cancers detected in the cohort of women diagnosed with classical mammography and ultrasound
• To describe molecular profiles of cancers detected only with ultrasound,

Enrollment: 203 patients

Sex: Female

Volunteers: No Healthy Volunteers

Inclusion criteria

• Women diagnosed with a breast cancer
• Detection of a breast cancer during the screening campaign organized between june 2015 and july 2018 in the following geographic zones : Cantal, Haute Loire and Puys de Dôme

Exclusion criteria

• Patients who expressed their opposition to the use of their personal data

Trial design

203 participants in 2 patient groups

Breast cancers cases diagnosed with tomosynthesis and ultrasound

Brest cancers cases diagnosed with mammography and ultrasound