Consumer Assessment of Tobacco Flavor and Odor

Roswell Park Comprehensive Cancer Center

Status: Terminated

Conditions: Healthy Subject; Current Vaper

Treatments: Other: Questionnaire Administration; Behavioral: Behavioral Intervention

Study type: Observational

Funder types: Other; NIH

Identifiers

NCT04358315

U54CA228110 (U.S. NIH Grant/Contract)

NCI-2019-06320 (Registry Identifier)

I 80518 (Other Identifier)

Details and patient eligibility

About

This trial studies consumer assessments of tobacco flavor and odor. This study will compare the ability of expert and consumer panels to identify and characterize flavors, determine threshold detection levels for individual and mixed flavors, and identify the dominant flavor of mixtures.

Full description

PRIMARY OBJECTIVE:

I. Develop consumer (untrained) sensory panels to identify and assess characterizing flavors in electronic (e)-liquids.

OUTLINE:

Non-user panelists smell and user panelists puff flavored e-liquids and answer questions about the products.

Enrollment: 29 patients

Sex: All

Ages: 21 to 55 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• CONSUMER USER: Current daily vapers of products containing nicotine
• CONSUMER USER: No concurrent use of other tobacco products
• CONSUMER USER: General good health
• CONSUMER USER: No allergies
• CONSUMER USER: No self-reported taste or smell deficits
• CONSUMER USER: Not pregnant or lactating
• CONSUMER USER: No medications known to interfere with taste/smell
• CONSUMER USER: Passing scores on the Brief Smell Identification Test (B-SIT), phenylthiocarbamine (PTC) and 6-n-propylthiouracil (PROP) smell and taste tests
• CONSUMER USER: No positive diagnosis of COVID-19 within 30 days
• CONSUMER NONUSER: No use of tobacco or nicotine products in the last year
• CONSUMER NONUSER: General good health
• CONSUMER NONUSER: No allergies
• CONSUMER NONUSER: No self-reported taste or smell deficits
• CONSUMER NONUSER: Not pregnant or lactating
• CONSUMER NONUSER: No medications known to interfere with taste/smell
• CONSUMER NONUSER: Passing scores on the Brief Smell Identification Test (B-SIT), phenylthiocarbamine (PTC) and 6-n-propylthiouracil (PROP) smell and taste tests
• CONSUMER NONUSER: No positive diagnosis of COVID-19 within 30 days

Exclusion criteria

• CONSUMER USER: Outside age range
• CONSUMER USER: Not current daily vapers
• CONSUMER USER: Concurrent use of other tobacco products
• CONSUMER USER: Fair or poor general health
• CONSUMER USER: Allergies
• CONSUMER USER: Self-reported taste or smell deficits
• CONSUMER USER: Pregnant or lactating
• CONSUMER USER: Medications known to interfere with taste/smell
• CONSUMER USER: Failing scores on the Brief Smell Identification Test (B-SIT), phenylthiocarbamine (PTC) and 6-n-propylthiouracil (PROP) smell and taste tests
• CONSUMER USER: Positive diagnosis of COVID-19 within 30 days
• CONSUMER NONUSER: Outside age range
• CONSUMER NONUSER: Use of tobacco or nicotine products in the last year
• CONSUMER NONUSER: Fair or poor general health
• CONSUMER NONUSER: Allergies
• CONSUMER NONUSER: Self-reported taste or smell deficits
• CONSUMER NONUSER: Pregnant or lactating
• CONSUMER NONUSER: Medications known to interfere with taste/smell
• CONSUMER NONUSER: Failing scores on the Brief Smell Identification Test (B-SIT), phenylthiocarbamine (PTC) and 6-n-propylthiouracil (PROP) smell and taste tests
• CONSUMER NONUSER: Positive diagnosis of COVID-19 within 30 days

Trial design

29 participants in 1 patient group

Observational (smell or puff e-liquids)

Description:

All panel participants smell and user panelists puff flavored e-liquids and answer questions about the products.

Treatment:

Behavioral: Behavioral Intervention

Other: Questionnaire Administration