Contegra Versus Pulmonary Homograft for Right Ventricular Outflow Tract Reconstruction in Newborns

Queen Fabiola Children's University Hospital

Status: Completed

Conditions: Right Ventricular Outflow Tract Reconstruction; Congenital Heart Defect

Treatments: Procedure: right ventricular outflow tract reconstruction with contegra; Procedure: right ventricular outflow tract reconstruction with pulmonary homograft

Study type: Observational

Funder types: Other

Identifiers

NCT03348397

P2016/Cardio/RVOTtherapy

Details and patient eligibility

About

Pulmonary homografts are standard substitutes for right ventricular outflow tract reconstruction in congenital heart surgery. Unfortunately shortage and conduit failure secondary to early calcifications and shrinking are observed particularly for small sized conduits in younger patients. In neonates, Contegra® 12mm could be a valuable alternative, but conflicting evidence exists. This retrospective study compared the outcome of these two conduits in a newborn population.

Enrollment: 53 patients

Sex: All

Ages: Under 30 days old

Volunteers: No Healthy Volunteers

Inclusion criteria

neonatal patients who had a reconstruction of the right ventricular outflow tract with a pulmonary homograft or a Contegra between January 1992 and December 2014 at HUDERF

Exclusion criteria

NA

Trial design

53 participants in 2 patient groups

Contegra patients

Treatment:

Procedure: right ventricular outflow tract reconstruction with contegra

Pulmonary homograft patients

Treatment:

Procedure: right ventricular outflow tract reconstruction with pulmonary homograft