Contextualizing & Responding to HIV Risk Behaviors

Columbia University

Status: Completed

Conditions: Human Immunodeficiency Virus

Treatments: Behavioral: MACE; Behavioral: Project ADHERE

Study type: Interventional

Funder types: Other; NIH

Identifiers

NCT03300908

AAAL7007

K01DA036411 (U.S. NIH Grant/Contract)

Details and patient eligibility

About

The purpose of this study was to pilot test the potential for improvement in antiretroviral medication adherence of a an adapted group-based, multi-session, community-based Antiretroviral Therapy (ART) adherence and risk reduction intervention, Project ADHerence Education and Risk Evaluation (ADHERE). Project ADHERE was compared to a single-session group-based medication adherence intervention, Medication Adherence and Care Engagement (MACE).

A secondary aim was to examine the impact of Project ADHERE on HIV risk behaviors (i.e., illicit drug use and unprotected sexual behavior).

This study was designed to inform, design, and pilot test the two antiretroviral medication adherence interventions for HIV-infected formerly incarcerated individuals.

Full description

Formerly incarcerated Black drug offenders are at an elevated risk for HIV infection. Despite substantial research expressing the need for HIV prevention services for ex-offenders postrelease, this population has limited access to quality programming and services related to HIV risk reduction. This K01 application seeks to inform and adapt an HIV risk reduction intervention to address the needs of formerly incarcerated Black drug offenders who are being released from prisons in the New York City metropolitan area.The study will utilize qualitative and quantitative methods to inform and adapt an HIV prevention intervention for this study population.

Enrollment: 32 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

1. ≥18 years of age
2. HIV seropositive with "detectable" viral load (VL)(defined as >50 copies/mL)
3. history of drug use (used illicit drugs within the past year)
4. experienced incarceration in prison or jail within the past five years

Exclusion criteria

1. living in a healthcare or assisted living facility
2. experienced incarceration longer than five years ago

Trial design

Primary purpose: Supportive Care

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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32 participants in 2 patient groups

Project ADHERE

Experimental group

Description:

Participants will receive a 3-session antiretroviral medication adherence and risk reduction intervention called Project ADHERE.

Treatment:

Behavioral: Project ADHERE

Control MACE

Active Comparator group

Description:

Participants will receive a one-session antiretroviral medication adherence intervention called MACE.

Treatment:

Behavioral: MACE