Continous Assessment of Cerebral Autoregulation With Near-infrared Spectroscopy

Yu Liyun

Status: Unknown

Conditions: Cerebral Blood Flow; Cerebral Perfusion Pressure

Treatments: Device: measure TOI and BP

Study type: Observational

Funder types: Other

Identifiers

NCT02959008

111

Details and patient eligibility

About

Cerebral autoregulation can be explained by a tight coupling between oxygen supply and demand of the brain, and is essential to maintain a constant cerebral blood flow (CBF) in the context of changes in cerebral perfusion pressure. In this study, investigators use Near-infrared spectroscopy (NIRS) to monitor cerebral autoregulation.

Full description

Near-infrared spectroscopy (NIRS) is a noninvasive technology that real-time monitors cerebral tissue oxygenation index (TOI). Investigators use Near-infrared spectroscopy (NIRS) to monitor cerebral autoregulation of hypertensive participants and non-hypertensive participants.

Enrollment: 40 estimated patients

Sex: All

Ages: 18 to 80 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• health people, or people with hypertension

Exclusion criteria

• diabetes, anemia, liver disease, kidney disease.

Trial design

40 participants in 2 patient groups

normal

Description:

Human without hypertension, diabetes, anemia, liver disease and kidney disease. The group will measure TOI and BP.

Treatment:

Device: measure TOI and BP

hypertension

Description:

Human only have hypertension, without diabetes, anemia, liver disease and kidney disease. Hypertension group will measure TOI and BP.

Treatment:

Device: measure TOI and BP