Continous Quadratus Lumborum Block for Hepatic Surgery With Right Subcostal Incision

Cui Xulei

Status: Terminated

Conditions: Nerve Block; Hepatectomy; Analgesia

Treatments: Procedure: Continous QLB (quadratus lumborum block); Drug: Morphine given as IPCA; Drug: Ropivacaine; Device: Philip CX50 Ultrasound Scanner

Study type: Interventional

Funder types: Other

Identifiers

NCT02914015

CXL4

Details and patient eligibility

About

This prospective, randomized study, control study aims to compare the analgesic effect, opioids consumption, quality of recovery, length of hospital stay and et al. between unilateral continuous quadratus lumborum block (QLB) and intravenous patient-controlled analgesia (IPCA) alone in patients undergoing hepatectomy with right J-shape subcostal incision.

Enrollment: 40 patients

Sex: All

Ages: 18 to 70 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Age 18-70 yrs
• American Society of Anesthesiologists physical statusⅠ-Ⅲ
• Undergo hepatectomy with right J-shape subcostal incision
• Informed consent

Exclusion criteria

• A known allergy to the drugs being used
• Coagulopathy, on anticoagulants
• Analgesics intake, history of substance abuse
• Participating in the investigation of another experimental agent
• Inability to properly describe postoperative pain to investigators (eg, language barrier, neuropsychiatric disorder)

Trial design

Primary purpose: Supportive Care

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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40 participants in 2 patient groups

Continuous QLB+postoperative IPCA

Experimental group

Description:

Single-injection of QLB (quadratus lumborum block) is given preoperatively followed with continuous infusion+ postoperative IPCA (intravenous patient control analgesia)

Treatment:

Drug: Morphine given as IPCA

Device: Philip CX50 Ultrasound Scanner

Drug: Ropivacaine

Procedure: Continous QLB (quadratus lumborum block)

IPCA

Active Comparator group

Description:

Postoperative IPCA (intravenous patient control analgesia) is given alone

Treatment:

Drug: Morphine given as IPCA