Continous Renal Replacement Therapy With the CARPEDIEM® in a French National Cohort of 25 Neonates and Small Infants

Centre Hospitalier Universitaire de Nice

Status

Completed

Conditions

Kidney Diseases

Cardiac Disease

Pulmonary Disease

Metabolic Disease

Twin to Twin Transfusion Syndrome

Hypoxic-Ischemic Encephalopathy

Sepsis

Treatments

Device: CARPEDIEN

Study type

Observational

Funder types

Other

Identifiers

NCT05495607

22-NEPHRO-01

Details and patient eligibility

About

Historically, CKRT and hemodialysis were performed in small infants and newborns with devices developed for adults with high rates of complications and mortality.

We aim to retrospectively report the first multicenter French experience of CARPEDIEM® use and evaluate the efficacy, feasibility, outcomes, and technical considerations of this new device in a population of neonates and small infant. Compared to adult's device continuous renal replacement therapy with an adapted machine allowed successful blood purification without severe complications even in low birth weight neonates.

Enrollment

25 patients

Sex

All

Ages

Under 3 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

Children and neonates including premature and low birth weight neonates
Have a diagnosis of acute kidney injury, end stage renal disease, metabolic disease, electrolyte abnormality
Require renal replacement therapy

Exclusion criteria

-Renal replacement therapy with another device than Carpediem machine