Continuous and Discontinuous Determination of Propofol Concentration in Breathing Gas

University of Luebeck

Status: Completed

Conditions: General Anesthesia

Study type: Observational

Funder types: Other

Identifiers

NCT00532402

P-A-S-1

Details and patient eligibility

About

This study should compare the propofol concentration in breathing gas and in plasma (before and) after lung passage. Propofol concentrations in breathing gas are continuously measured by a sensor. For comparison a discontinuous method is used. Neurophysiologic parameters for determination of depth of anesthesia are compared to the continuous measured propofol concentration in breathing gas.

Study hypothesis: continuous measured propofol concentration in breathing gas correlates to propofol concentration in plasma and depth of anaesthesia.

Enrollment: 16 estimated patients

Sex: All

Ages: 18 to 90 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patient destined for general anesthesia

Exclusion criteria

• Heart insufficiency NYHA IV
• Allergy to propofol