Continuous Glucose Monitoring in Critically Ill Patients

Medical University of Vienna

Status: Completed

Conditions: Critical Illness

Treatments: Device: continuous subcutaneous glucose monitoring

Study type: Interventional

Funder types: Other

Identifiers

NCT00494455

108/2005

Details and patient eligibility

About

The purpose of this study is to determine whether subcutaneous continuous glucose monitoring in critically ill patients is clinically feasible accurate and reliable.

Full description

Hyperglycemia is is associated with more complications and higher morbidity and mortality in critically ill patients. Therefore, strict glycemic control with a target blood glucose level between 80 and 110 mg/dl is recommended. Intensive insulin therapy requires continuous intravenous insulin infusion according to an algorithm and frequent blood glucose measurements. Implementation of intensive insulin therapy increases workload for both physicians and especially for nurses.

Continuous glucose measurement would facilitate blood glucose control in critically ill patients. Numerous studies have shown accuracy of the subcutaneous continuous glucose monitoring derived glucose values compared to blood glucose measurements in diabetics. Studies evaluating the subcutaneous continuous glucose monitoring in an inpatient-population especially in an ICU-setting are rare. Therefore the aim of this study is the prospective evaluation of continuous subcutaneous glucose monitoring in critically ill patients with circulatory shock demanding norepinephrine therapy as compared to critically ill patients without shock.

Enrollment: 50 patients

Sex: All

Ages: 19+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Admitted patients expected to stay >48h either with circulatory shock requiring norepinephrine therapy or without circulatory shock.

Exclusion criteria

• Admitted patients expected to stay <48h

Trial design

Primary purpose: Supportive Care

Allocation: Non-Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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50 participants in 2 patient groups

1

Active Comparator group

Description:

Continuous subcutaneous glucose monitoring in patients without shock

Treatment:

Device: continuous subcutaneous glucose monitoring

Device: continuous subcutaneous glucose monitoring

2

Active Comparator group

Description:

continuous subcutaneous glucose monitoring in patients with shock

Treatment:

Device: continuous subcutaneous glucose monitoring

Device: continuous subcutaneous glucose monitoring