Continuous Glucose Monitoring to Aid Weight Loss in Prediabetes

Stanford University

Status: Terminated

Conditions: Weight Loss; PreDiabetes

Treatments: Other: Dietitian; Device: CGM

Study type: Interventional

Funder types: Other; NIH

Identifiers

NCT03844646

P30DK116074 (U.S. NIH Grant/Contract)

49402

Details and patient eligibility

About

The primary objective of this study is to determine whether intermittent use of continuous glucose monitor will facilitate weight loss in individuals who are overweight/obese with prediabetes.

Full description

Continuous glucose monitoring (CGM) has revolutionized the treatment of patients on intensive insulin therapy and its utility can also be harnessed to help individuals with prediabetes make healthful lifestyle changes. Successful weight loss requires adherence to lower calories, regular exercise, and self-monitoring. This proposal will test the hypothesis that intermittent CGM will facilitate all of these components for successful weight loss by functioning as a continuous self-monitor and guiding healthful food choices and physical activity.

Enrollment: 12 patients

Sex: All

Ages: 18 to 99 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Overweight/obese (BMI 25-40 kg/m2)
• Prediabetes (fasting glucose 100-125 mg/dL and/or HbA1c 5.7-6.4%)

Exclusion criteria

• On glucose-lowering medications (e.g., metformin)
• On weight-loss medications

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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12 participants in 2 patient groups

CGM plus dietitian

Experimental group

Description:

Intermittent use of a continuous glucose monitor (CGM) plus dietitian support

Treatment:

Other: Dietitian

Device: CGM

Dietitian only

Other group

Description:

Dietitian support only

Treatment:

Other: Dietitian