Continuous Non-invasive Hemodynamic Monitoring in Early-onset Severe Preeclampsia: a Comparison of Echocardiography, Bioreactance, and Finger Cuff Measurements

Yale University

Status: Completed

Conditions: Pre-Eclampsia

Treatments: Diagnostic Test: Echocardiogrpahy and non-invasive monitoring

Study type: Observational

Funder types: Other

Identifiers

NCT05299229

2000028142

Details and patient eligibility

About

The purpose of this study is to compare the feasibility and accuracy of two methods of non-invasive hemodynamic assessments - bioreactance as assessed by non-invasive cardiac output monitoring (NICOM; Cheetah Medical) and pulse wave analysis as assessed by finger cuff arterial pressure (ClearSite, Edwards Life Sciences) - compared to hemodynamic assessments by intermittent echocardiography in early onset preeclampsia.

Enrollment: 12 patients

Sex: Female

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• BP >160 or DBP >110
• gestational age between 20-34 weeks
• singleton pregnancy

Exclusion criteria

• prior diagnosis of chronic hypertension or hypertensive disorder of pregnancy
• multi-fetal pregnancy

Trial design

12 participants in 1 patient group

Heart and vascular function

Description:

All study participants will have echocardiography and non-invasive monitoring by chest/back sensors and a finger cuff to determine the best method of monitoring heart and vascular function in preeclampsia.

Treatment:

Diagnostic Test: Echocardiogrpahy and non-invasive monitoring