Continuous Pre-peritoneal Wound Infiltration Versus Epidural Analgesia in Cancer Surgery

Assiut University

Status: Completed

Conditions: Abdominal Neoplasms

Treatments: Device: preperitoneal catheter; Device: epidural catheter

Study type: Interventional

Funder types: Other

Identifiers

NCT03002909

369

Details and patient eligibility

About

the investigators aim is to investigate the effect of continuous preperitoneal bupivacaine wound infiltration versus epidural analgesia on the inflammatory cytokines response following radical cytectomy

Enrollment: 40 patients

Sex: All

Ages: 18 to 60 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• ASA I-III patients
• aged 18-60 yr
• undergo open abdominal cancer surgery

Exclusion criteria

• general contraindications for epidural analgesia,
• recent history (8 weeks) of, chemotherapy or radiation,
• chronic opioid use

Trial design

Primary purpose: Health Services Research

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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40 participants in 2 patient groups

epidural group

Active Comparator group

Description:

an epidural catheter will be inserted under sterile conditions through the T9- 12 interspace using the 'loss-of-resistance' technique. The catheter will be advanced 4 cm cephalad. .

Treatment:

Device: epidural catheter

preperitoneal group

Active Comparator group

Description:

preperitoneal catheters will be placed in the subfascial (ie, pre-peritoneal) space under direct vision.

Treatment:

Device: preperitoneal catheter