Continuous Regional Analgesia After Total Knee Arthroplasty

Nantes University Hospital (NUH)

Status and phase: Completed; Phase 3

Conditions: Analgesia

Treatments: Other: NaCl 0.9%; Other: Glucose 5%

Study type: Interventional

Funder types: Other

Identifiers

NCT00337597

BRD 05/7-F

Details and patient eligibility

About

This prospective, comparative and double blind study is aimed to determine if normal saline or dextrose 5% in water will modify the stimulation during the insertion of the stimulating catheter used for continuous femoral and sciatic blocks in total knee replacement.

Full description

The operator is blinded to the medium fluid to expand the perineural femoral and sciatic nerves before threading in the stimulating catheter. He records all the electric data of electrolocation of nerve, which will be compared to determine whether or not a difference in intensity is found between normal saline or dextrose 5% in water.

Enrollment: 50 patients

Sex: All

Ages: 18 to 90 years old

Volunteers: No Healthy Volunteers

Inclusion and exclusion criteria

Inclusion Criteria:

• American Society of Anesthesiologists (ASA) I and II
• Male or non-pregnant female
• 18 - 80 years of age
• Not allergic to iodine or local anesthetics
• Absence of abnormality of coagulation
• Scheduled for total knee replacement

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind