Continuous Versus Conventional Volume Management During CRRT (Continuous Renal Replacement Therapy)

Dallas VA Medical Center

Status: Completed

Conditions: Continuous Renal Replacement Therapy

Treatments: Device: use of blood volume monitoring device in conjunction with machine used for continuous renal replacement to assess and determine volume removal; Device: use of continuous renal replacement machine for renal replacement

Study type: Interventional

Funder types: Other U.S. Federal agency

Identifiers

NCT01405092

#09-097

Details and patient eligibility

About

Use of on-line blood volume monitoring during continuous renal replacement therapy can improve volume management in acute kidney injury patients requiring renal replacement

Enrollment: 28 patients

Sex: All

Ages: 21+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients with kidney injury requiring continuous renal replacement therapy and volume removal

Exclusion criteria

• unable to provide or obtain patient consent
• not expected to survive 48 hours

Trial design

Primary purpose: Supportive Care

Allocation: Randomized

Interventional model: Crossover Assignment

Masking: None (Open label)

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28 participants in 2 patient groups, including a placebo group

Standard volume management

Placebo Comparator group

Description:

patients on this arm will receive usual care volume management during continuous renal replacement therapy

Treatment:

Device: use of continuous renal replacement machine for renal replacement

continuous volume management

Active Comparator group

Description:

use of Critline, Hemametrics USA, in conjunction with continuous renal replacment therapy to determine volume removal

Treatment:

Device: use of blood volume monitoring device in conjunction with machine used for continuous renal replacement to assess and determine volume removal

Device: use of continuous renal replacement machine for renal replacement