Continuous Versus Intermittent Bolus Infusion of Paravertebral Blocks for Thoracic Surgery

Mayo Clinic

Status: Completed

Conditions: Thoracic Diseases

Treatments: Other: Continuous Infusion; Other: Programmed Intermittent Bolus

Study type: Interventional

Funder types: Other

Identifiers

NCT03480984

17-009991

Details and patient eligibility

About

The researchers are trying to determine pain medication consumption in the first 24 hours after surgery in patients given the standard continuous infusion of local anesthetic versus patients given the same total dose via programmed intermittent dosing. Both groups will receive the option of patient controlled pain medication as well as the same dose of pre-programmed pain medication. The only difference is the rate of administration: continuous vs. hourly intervals.

Enrollment: 50 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Documentation of planned thoracic surgery for which a paravertebral catheter is indicated based on surgeon request as well as appropriateness of location of surgical site.
• Ability for subject to comply with the requirements of the study.

Exclusion criteria

• Pregnancy.
• Coagulopathy at time of evaluation or surgery.
• Infection at the site of needle insertion.
• Allergy to local anesthetic.
• Patient refusal.
• Chronic opioid use

Trial design

Primary purpose: Other

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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50 participants in 2 patient groups

Programmed Intermittent Bolus

Active Comparator group

Description:

6 mL 0.2% ropivacaine hourly, starting on arrival to PACU, given via an hourly programmed bolus

Treatment:

Other: Programmed Intermittent Bolus

Continuous Infusion

Active Comparator group

Description:

6 mL 0.2% ropivacaine hourly, starting on arrival to PACU, given via continuous infusion

Treatment:

Other: Continuous Infusion