Contraception in Normal and Subnormal Men

University Hospital Muenster

Status and phase: Terminated; Phase 2

Conditions: Healthy

Treatments: Drug: injection of hormonal male contraceptive

Study type: Interventional

Funder types: Other

Identifiers

NCT00167141

IRM 2003/21

Details and patient eligibility

About

Volunteers with normal and subnormal semen parameters receive a hormonal male contraceptive in order to investigate whether there are differences between normal and subnormal men in terms of suppressibility, rate of azoospermia and reversibility of suppression of spermatogenesis.

Full description

Volunteers with normal and subnormal semen parameters receive a hormonal male contraceptive in order to investigate whether there are differences between normal and subnormal men in terms of suppressibility, rate of azoospermia and reversibility of suppression of spermatogenesis. Twenty-five men will be recruited for each group. They will be exposed to hormonal male contraception for six months.

Enrollment: 41 patients

Sex: Male

Ages: 20 to 50 years old

Volunteers: Accepts Healthy Volunteers

Inclusion and exclusion criteria

Inclusion Criteria:

• Volunteers with normal and subnormal semen parameters

Trial design

Primary purpose: Treatment

Allocation: Non-Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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41 participants in 1 patient group

testosterone injections

Experimental group

Description:

injections of testosterone to normal men (arm 1) and two men with subnormal semen parameters (arm 2)

Treatment:

Drug: injection of hormonal male contraceptive