Contrast-associated Acute Kidney Injury in Patients With Different Types of Coronary Artery Disease

I.M. Sechenov First Moscow State Medical University

Status: Completed

Conditions: Coronary Artery Disease; NSTEMI - Non-ST Segment Elevation MI; Angina, Stable; Acute Kidney Injury; Angina, Unstable; STEMI - ST Elevation Myocardial Infarction; Contrast-induced Nephropathy

Treatments: Other: Iodinated contrast

Study type: Observational

Funder types: Other

Identifiers

NCT04163484

11/2019

Details and patient eligibility

About

The goal of the study is to assess the prevalence of contrast-associated acute kidney injury in patients with stable coronary artery disease, ST-elevation myocardial infarction and unstable angina/NSTEMI, assess the risk factors of contrast-induced acute kidney injury development and the influence of contrast-induced kidney injury on 1-year prognosis.

Enrollment: 156 patients

Sex: All

Ages: 18 to 80 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Males and females aged 18-80
• Stable CAD receiving optimal medical treatment requiring PCI or STEMI or NSTEMI
• Intra-arterial injection of iodinated contrast media
• Informed consent

Exclusion criteria

• Age less than 18
• Pregnancy, lactation
• Refuse to sign the informed consent
• Contraindications for PCI
• Other conditions affecting prognosis (oncology, liver failure etc)
• CKD stage 4-5
• Patients receiving nephrotoxic drugs

Trial design

156 participants in 3 patient groups

Stable coronary artery disease

Treatment:

Other: Iodinated contrast

ST-elevation myocardial infarction

Treatment:

Other: Iodinated contrast

Non-ST-elevation myocardial infarction

Treatment:

Other: Iodinated contrast