Contrast Enhanced Ultrasonography (CEUS) of Patients With Crohn's Disease

Haukeland University Hospital

Status: Terminated

Conditions: Crohn's Disease

Study type: Observational

Funder types: Other; Industry

Identifiers

NCT01074580

22209

Details and patient eligibility

About

The purpose of this study is investigate if high frequency sonography and contrast enhanced sonography can be used to predict remission in patients with deterioration of Crohn's disease treated with steroids or tumor necrosis factor (TNF) alfa inhibitors.

Enrollment: 20 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Deterioration of Crohn's disease
• CDAI>150
• Treated with systemic steroids or TNF alfa inhibitors
• Lesion found on ultrasound

Exclusion criteria

• Disease location not reachable with ileocolonoscopy
• Pregnancy
• Acute coronary disease
• Unstable coronary disease
• Previous allergic reaction to SonoVue or its components

Trial design

20 participants in 1 patient group

Deterioration, Crohn's disease

Description:

Patients \> 18 years old with a deterioration of Crohn's disease defined by CDAI \>150 and requiring treatment with systemic steroids or TNF alfa inhibitors