Contrast Nephropathy in Type 2 Diabetes (VCG4)

Fayoum University

Status: Completed

Conditions: Diabetes; Kidney Function Affection Upon Exposure to Radiocontrast; Microalbuminuria

Treatments: Drug: Linagliptin Oral Tablet

Study type: Observational

Funder types: Other; Industry

Identifiers

NCT03470454

VCG 4

Details and patient eligibility

About

To study the effect of radiocontrast material on kidney functions in diabetics with microalbuminuria

Full description

Study design:

This study will be an observational prospective cohort study.

Study population:

Diabetics undergoing any intervention using radiocontrast material for any medical indication in Fayoum universiy hospital will be selected. There will be two arms of the study,each arm will contain 20 patients first arm diabetics on linagelptin, second arm diabetics on other DPP4 inhibitors.

Data collection:

Patients will be subjected to; full clinical examination,waist hip ratio assessment,BMI assessment fasting blood glucose,Serum uric acid, urine ACR, eGFR will be done before and after the investigation.

Enrollment: 40 patients

Sex: All

Ages: 21+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Diabetics on DPP 4 inhibitor treatment

Exclusion criteria

• Diabetics on insulin

Trial design

40 participants in 2 patient groups

diabetics on linagelptin

Description:

Diabetic patients were given linagelptin for blood glucose control

Treatment:

Drug: Linagliptin Oral Tablet

diabetics on other DPP4 inhibitors

Description:

Diabetic pateints were given other DPP4 inhibitors eg: vlidagliptin for blood glucose control

Treatment:

Drug: Linagliptin Oral Tablet