Contributing Factors to Anterior Resection Syndrome and Its Impact on Quality of Life: A Retrospective Cohort Study

University of Malta

Status: Completed

Conditions: Quality of Life; Cancer; Low Anterior Resection Syndrome

Treatments: Procedure: anterior resection

Study type: Observational

Funder types: Other

Identifiers

NCT04114591

S07/18

Details and patient eligibility

About

This study adds to the understanding of the contributing factors leading to LARS, the long term effects of this syndrome post-operatively and its impact on quality of life.

Enrollment: 179 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• All adult patients >18 years, under the care of all surgical firms at Mater Dei Hospital, who had undergone anterior resection for rectal cancer between January 2014 and December 2016

Exclusion criteria

• colorectal cancer (>15cm) from anal verge
• permanent stoma
• known disseminated or recurrent disease,
• patient without restitution of bowel continuity after 1 year

Trial design

179 participants in 2 patient groups

LARS symptoms

Description:

Patient suffering from LARS as identified through LARS questionnaire

Treatment:

Procedure: anterior resection

No LARS symptoms

Description:

Absence of LARS symptoms

Treatment:

Procedure: anterior resection