Contribution of MRI in the Evaluation of Apparent Diffusion Coefficient and Prediction of Response to Neoadjuvant Chemotherapy in Breast Cancer (ADC)

Centre Jean Perrin

Status

Withdrawn

Conditions

Assess the Variation of Apparent Diffusion Coefficient

Treatments

Other: MRI (Magnetic resonance imaging)

Study type

Interventional

Funder types

Other

Identifiers

NCT01956513

Etude ADC

Details and patient eligibility

About

The main objective of the study is to assess the sensitivity and the specificity of the variation of apparent diffusion coefficient for prediction, after a course of neoadjuvant chemotherapy or after modification of the treatment sequence, the pathological response at the end of chemotherapy

Sex

Female

Ages

18+ years old

Volunteers

No Healthy Volunteers

Inclusion criteria

Age> 18 years.
Patient suffering from a breast tumor, regardless of the stage and size
Patient requiring neoadjuvant chemotherapy
Patient has the ability to undergo 18F-FDG-PET at baseline, at end of cycle 1 and at the end of neoadjuvant treatment before surgery
Compulsory affiliation to a social security system.
Obtaining informed consent in writing, signed and dated.

Exclusion criteria

Patient with cognitive or psychiatric disorders.
Patient deprived of liberty by a court or administrative.
Patient with signs against the achievement of MRI, mammography and ultrasound
Patient metastatic
Patient with prior chemotherapy, radiotherapy and hormone therapy for her breast cancer
Pregnant women, current lactation
Patient suffering from uncontrolled diabetes (> 11 mmol / L)