Contribution of the Somatosensory System to Speech Perceptual Processing

Yale University

Status: Terminated

Conditions: Consolidation; Speech

Treatments: Behavioral: Facial Skin Stretch; Behavioral: Adaptation

Study type: Interventional

Funder types: Other; NIH

Identifiers

NCT04818021

R01DC017439 (U.S. NIH Grant/Contract)

2000025475_b

Details and patient eligibility

About

These studies test the hypothesis that the repeated pairing of somatosensory inputs with speech sounds, such as occurs during speech motor learning, results in changes to the perceptual classification of speech sounds.

Full description

This study will assess changes to the perceptual classification of speech sounds that are related to repeated pairing of somatosensory and auditory inputs (as would occur during speech motor learning). Before and after the training, base-line and post-training auditory perceptual performance will be examined in the absence of somatosensory stimulation, in order to evaluate the effects of the pairing on speech perception. Perceptual classification and speech motor learning will both be assessed on a 0 to 100 scale.

Enrollment: 160 patients

Sex: All

Ages: 21 to 40 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• right handed adults
• no known physical or neurological abnormalities

Exclusion criteria

• patients with:
• cardiac pacemaker
• surgical clips or values on the heart
• implants
• metal or metallic fragments in any part of the body
• pregnancy
• claustrophobia
• a personal or family history of epilepsy
• currently taking antipsychotic drugs
• currently taking antidepressant drugs
• currently taking antianxiety drugs.

Trial design

Primary purpose: Basic Science

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

---

160 participants in 4 patient groups

Adaptation to Altered Auditory Feedback

Experimental group

Description:

Adaptation to Altered Auditory Feedback

Treatment:

Behavioral: Adaptation

Adaptation to Altered Auditory Feedback + Forward Skin Stretch

Experimental group

Description:

Adaptation to Altered Auditory Feedback + Forward Skin Stretch

Treatment:

Behavioral: Adaptation

Behavioral: Facial Skin Stretch

Adaptation to Altered Auditory Feedback + Backward Skin Stretch

Experimental group

Description:

Adaptation to Altered Auditory Feedback + Backward Skin Stretch

Treatment:

Behavioral: Adaptation

Behavioral: Facial Skin Stretch

Speech Repetition Control

Experimental group

Description:

Speech Repetition Control

Treatment:

Behavioral: Adaptation