Control of MRSA in Nursing Homes: Decolonization vs Standard Precautions

Lausanne University Hospital (CHUV)

Status: Completed

Conditions: Methicillin-Resistant Staphylococcus Aureus

Treatments: Other: intervention

Study type: Interventional

Funder types: Other

Identifiers

NCT01138462

Protocole 96/10

Details and patient eligibility

About

The purpose of this study is to determine the better approach between the currently procedure (i.e. standards precautions) and a reinforced strategy to control MRSA transmission in the institutionalized population of nursing homes in Canton of Vaud, Switzerland.

Full description

MRSA carriage among nursing homes residents of Canton Vaud, Switzerland, is increasing, despite use of standard precautions. Recommendation to prevent MRSA transmission in long term care facilities are lacking. We aim to reinforce the current infection control strategy by general MRSA screening of institutionalised residents and decolonisation of MRSA carriers. Because the uncertainties in the impact of this reinforced strategy, we aim to compare this action to the policy actually applied.

Enrollment: 157 patients

Sex: All

Ages: 18+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• all nursing homes of canton Vaud, Switzerland, that give the consent of participation

Exclusion criteria

• refusal to participate

Inclusion criteria for decolonisation in intervention nursing homes:

• all MRSA positive residents living in a Nursing Home included in the intervention group

Exclusion Criteria for decolonisation:

• residents that refuse to be screened or refused the decolonisation
• life expectancy shorter of 7 days
• known intolerance of disinfectant/ topical antibiotics used in the protocol
• active MRSA infection
• asymptomatic MRSA bacteriuria
• stage IV wound (according to National Pressure Ulcer Advisory Panel)

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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157 participants in 2 patient groups

Standard Precautions

No Intervention group

Description:

control arm, standards precautions for all residents living in the nursing home of control arm, including MRSA carriers

Intervention

Other group

Description:

Intervention arm, standards precautions for all residents living in nursing homes of intervention arm, and topical decolonization for MRSA carriers, including environmental disinfection

Treatment:

Other: intervention