Control of Therapy of Acne Papulopustulosa by Visible Light With Waterfiltered Infrared and / or Adapalen (Differin Gel)

Technische Universität Dresden

Status and phase: Unknown; Phase 4

Conditions: Acne Papulopustulosa

Treatments: Radiation: VIS and wIRA; Drug: Adapalen

Study type: Interventional

Funder types: Other

Identifiers

NCT00237978

TUD-Akne02-003

Details and patient eligibility

About

The aim of the study is to investigate the effectivity of visible light in combination with waterfiltered infrared in treating acne papulopustulosa. The reduction of inflammatory and non-inflammatory lesions within 8 weeks will be measured and compared with the standard treatment with Adapalene.

Enrollment: 60 estimated patients

Sex: All

Ages: 14+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Mild to moderate acne papulopustulosa according to Burton Scale Stage 3 to 4
• At least 5 inflammatory and 5 non-inflammatory lesions in the face
• Age >= 14 years

Exclusion criteria

• pregnant and nursing women
• Antiandrogen therapy
• therapy with antibiotics within the last 4 weeks
• therapy with retinoids within the last 6 months
• natural or artificial UV-therapy within the last 4 weeks
• severe acne papulopustulosa according to Burton Scale 5 or 6
• Severe systemic condition
• Secondary acne

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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60 participants in 3 patient groups

1

Active Comparator group

Description:

VIS and wIRA

Treatment:

Radiation: VIS and wIRA

2

Active Comparator group

Description:

VIS, wIRA and Adapalen

Treatment:

Drug: Adapalen

Radiation: VIS and wIRA

3

Active Comparator group

Description:

Adapalen

Treatment:

Drug: Adapalen