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Conversion Surgery After Target Therapy or Immunotherapy in Stage IV Gastric Cancer

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Samsung Medical Center

Status

Completed

Conditions

Gastric Cancer Stage IV

Treatments

Drug: immune check point inhibitors (PD-1 inhibitors), target therapy (trastuzumab)

Study type

Observational

Funder types

Other

Identifiers

NCT07009600
SMC 2025-03-046-001

Details and patient eligibility

About

In this retrospective study, investigators conducted a comprehensive investigation of the factors influencing postoperative prognosis in patients with stage IV gastric cancer undergoing conversion surgery. Specifically, investigators examined the impact of targeted therapy or immune check point inhibitors (ICIs) in combination with preoperative chemotherapy on (1) prognostic differences based on initial progression (invading adjacent organs) and metastatic site (peritoneum, distant lymph node [LN]) at the time of stage IV gastric cancer diagnosis and (2) conversion surgery outcomes and pathological complete response (pCR).

Enrollment

124 patients

Sex

All

Volunteers

No Healthy Volunteers

Inclusion criteria

  • Stage IV gastric cancer patients who underwent conversion surgery

Exclusion criteria

  • Patients who did not undergo gastrectomy
  • Patients who underwent emergent surgery due to cancer perforation
  • Patients with missing medical records or information

Trial contacts and locations

0

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Data sourced from clinicaltrials.gov

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