Cord Blood Alarin Levels in Term Babies

Konya City Hospital

Status: Completed

Conditions: Birth Weight

Treatments: Diagnostic Test: Appropriate for gestational age , small for gestational age, large for gestational age, Baby of mother diagnosed with GDM

Study type: Observational

Funder types: Other

Identifiers

NCT06333548

KSH_MB_2024_1

Details and patient eligibility

About

In this study, alarin levels in the cord blood of babies with large birth weights will be compared with babies of normal weight. Thus, the investigators aimed to find out whether there is a relationship between babies' birth weights and alarin.

Full description

Studies have shown that the galanin neuropeptide family plays a role in regulating appetite, insulin resistance, obesity, hypertension and metabolism. Alarin is a peptide consisting of 25 amino acids. Current research shows that allerin plays an important role in the emergence and development of diabetes and obesity. There are studies that found that the serum alarin level increased significantly in patients with impaired glucose tolerance and type 2 diabetes mellitus. Additionally, studies have found that both non-obese and obese type 2 diabetes mellitus serum alarin levels increase.

Studies in the literature are related to adults, and there are no studies on alarin levels in newborn babies.

Based on the alarin studies available in the literature, the investigators determined whether there is a relationship between the alarin level and the baby's birth weight by comparing the alarin level in the cord blood of babies with a high birth weight according to their gestational age (both babies of diabetic mothers and babies of non-diabetic mothers) compared to babies whose birth weight is within the normal range. the investigators aimed to find it.

Enrollment: 87 patients

Sex: All

Ages: 1 to 5 minutes old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Babies given consent by their families
• Healthy babies

Exclusion criteria

• Babies with syndromic appearance or any accompanying disease
• Babies whose family does not give consent

Trial design

87 participants in 4 patient groups

Appropriate for gestational age

Description:

Appropriate for gestational age

Treatment:

Diagnostic Test: Appropriate for gestational age , small for gestational age, large for gestational age, Baby of mother diagnosed with GDM

small for gestational age

Description:

small for gestational age

Treatment:

Diagnostic Test: Appropriate for gestational age , small for gestational age, large for gestational age, Baby of mother diagnosed with GDM

large for gestational age

Description:

large for gestational age

Treatment:

Diagnostic Test: Appropriate for gestational age , small for gestational age, large for gestational age, Baby of mother diagnosed with GDM

Baby of mother diagnosed with GDM

Description:

Baby of mother diagnosed with gestational diabetes mellitus

Treatment:

Diagnostic Test: Appropriate for gestational age , small for gestational age, large for gestational age, Baby of mother diagnosed with GDM